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For Urgent Appointments Call - 909-312-3300
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IPMG Research

IPMG is excited to introduce our new research department.
We are looking forward to offering innovative and novel treatments in the studies we are offering at our Loma Linda location. Our research team is waiting to hear from you.

Schedule a Consultation
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Call 909-488-9116

Spravato Treatment

Esketamine Nasal Spray

For Treatment-Resistant Depression (TRD) & Major Depressive Disorder (MDD)
Schedule a Consultation
Click here
Call (909) 328 – 9597

What is Spravato Treatment?

FDA-approved prescription nasal spray

SPRAVATO® (esketamine nasal spray) is an FDA-approved prescription nasal spray, used along with an antidepressant taken orally to treat:

  • Adults with treatment-resistant depression (TRD)
  • Depressive symptoms in adults with major depressive disorder (MDD) with suicidal thoughts or actions

Esketamine is in a class of medications called NMDA receptor antagonists. It works by changing some naturally occurring chemicals in the brain, though the exact mechanism by which it exerts its antidepressant effect is unknown.

Spravato contains esketamine hydrochloride, which has a chemical formula that is a mirror image of ketamine. It is designated as a Schedule III controlled substance under the Controlled Substances Act.

Because of potential risk of serious side-effects, Spravato can only be administered by the Risk Evaluation and Mitigation Strategy (REMS) certified treatment center.

FAQ

Spravato nasal spray is indicated for the treatment of depression in conjunction with oral antidepressant in adults who have failed treatment with at least two antidepressants (treatment resistant depression). It is also indicated in adults with major depressive disorder with acute suicidal ideation or behavior.

If you are seeking treatment for any of the above indications and you are not at the risk of having serious side effects with Spravato, it may be a good treatment option for you.

Please schedule an appointment with one of our providers to determine whether Spravato would be a good treatment option for you.
No, you will continue to take your oral antidepressant medication as before. Spravato nasal spray is approved for the treatment of depression in conjunction with oral antidepressant medication
Depending on your insurance plan, your insurance may cover Spravato treatment. Blue Cross Blue Shield (BCBS), Medicare, and Aetna are some of the insurances that are currently covering Spravato treatment. Before starting treatment, our benefits verification team will determine eligibility and benefits with your insurance, including any out of pocket costs that you may incur during treatment. It may take 1-2 weeks to get approval for Spravato from your insurance.
Some patients taking Spravato may experience nausea or vomiting. You should avoid eating two hours before and drinking liquids 30 minutes before taking Spravato.

If you take a nasal corticosteroid or nasal decongestant medicine, take these medicines at least one hour before taking Spravato. You should also request a family member or friend to drive you to and back from each appointment.
Spravato is administered as a nasal spray by the patient under direct clinical supervision of the healthcare provider in the medical office setting. The provider will tell you how to use the device and how much Spravato to take.

After each administration, you will be monitored in the office for about 2 hours. If the provider decides that it’s safe for you to leave office, then you should have a family member or a friend drive you back home from office.
In most cases, the treatment lasts about 8 weeks. Spravato is administered twice per week in the first 4 weeks and once every week from week 5-8.

Depending on your progress, if further maintenance treatment is required, your healthcare provider will discuss treatment options with you.

Each Spravato administration appointment typically lasts about 2 hours.

Spravato contains esketamine hydrochloride, which has a chemical formula that is a mirror image of ketamine. It is designated as a Schedule III controlled substance under the Controlled Substances Act and therefore it may carry serious risk of abuse and misuse. Some patients may experience one or more of the following side effects with Spravato:

  • Sedation or sleepiness
  • Dizziness – fainting or spinning sensation
  • Dissociation – feeling disconnected from yourself, your thoughts, feelings, space and time (dissociation)
  • Increase in anxiety
  • Physical and psychological dependence
  • Nausea and vomiting
  • Increased blood pressure
  • Feeling drunk
  • Decreased sensitivity (numbness)
  • Lack of energy
  • Increased suicidal thoughts and actions
  • Difficulty in urination

Spravato is not recommended for patients with the history of treatment for ballooning or bulging blood vessels (aneurysms), bleeding due to brain injury, and hypersensitivity to esketamine or ketamine or ingredients in esketamine spray.

BOOK APPOINTMENT FOR SPRAVATO TREATMENT

You can also schedule directly by calling (909) 328–9597 during normal business hours. If this is an emergency, please call 911.

This appointment booking page is only for Spravato Treatment. Do not use this page to book for regular appointment.

    We are Inland Psychiatric Medical Group and we are located throughout Southern California. We are a collaborative of Psychiatrists and other mental health providers trained and qualified to help you along your mental health journey.

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    We are Inland Psychiatric Medical Group from Southern California, a collaborative practice of psychiatrists and therapists who are well trained and highly qualified to help with all the challenges you have to face. We work with adults, children, adolescents, families, and couples.

    © 2022 IPMG. All rights reserved.

    john-kohut

    John Kohut, MD

    Dr. Kohut is a board-certified psychiatrist who works with patients from age 22 to the elderly providing medication management for patients with symptoms of anxiety, depression, and post-traumatic stress disorder. Dr. Kohut enjoys the opportunity of working in conjunction with psychotherapists of all fields such as licensed clinical psychologist, licensed clinical social workers, and marriage and family therapists. He works with fellow clinicians on an outpatient basis but when necessary, refers to inpatient services and consultants in various inpatient facilities in the San Bernardino and surrounding areas. Dr. Kohut has been in psychiatric practice since 1971.

    Practicing locations :

    San Bernardino
    john-kohut

    John Kohut, MD

    Dr. Kohut is a board-certified psychiatrist who works with patients from age 22 to the elderly providing medication management for patients with symptoms of anxiety, depression, and post-traumatic stress disorder. Dr. Kohut enjoys the opportunity of working in conjunction with psychotherapists of all fields such as licensed clinical psychologist, licensed clinical social workers, and marriage and family therapists. He works with fellow clinicians on an outpatient basis but when necessary, refers to inpatient services and consultants in various inpatient facilities in the San Bernardino and surrounding areas. Dr. Kohut has been in psychiatric practice since 1971.

    Practicing locations :

    San Bernardino
    sigrid-formantes

    Sigrid Formantes, MD

    Dr. Sigrid Formantes is a Board-certified general psychiatrist. She earned her medical degree at the University of the Philippines and completed her general psychiatry residency at the Brookdale Hospital and Medical Center in New York. She has been in practice since 2008 seeing adults 18 years and older.

    Practicing locations :

    Redlands
    sigrid-formantes

    Sigrid Formantes, MD

    Dr. Sigrid Formantes is a Board-certified general psychiatrist. She earned her medical degree at the University of the Philippines and completed her general psychiatry residency at the Brookdale Hospital and Medical Center in New York. She has been in practice since 2008 seeing adults 18 years and older.

    Practicing locations :

    Redlands

    Benefit the rewards of being a part of our Mental Health Group Therapy.

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    Benefit the rewards of being a part of our Mental Health Group Therapy.

    To find out what Group Therapy is currently in session, fill out the form below and our team will reach out to you.

    Telepsych ensures you get better access to healthcare with a decreased wait time.

    To learn more, fill out the form below and our team will reach out to you.

    Telepsych ensures you get better access to healthcare with a decreased wait time.

    To learn more, fill out the form below and our team will reach out to you.